12th International Conference on Frontotemporal Dementias and 1st International Society for Frontotemporal Dementias Congress - Program

International Society for Frontotemporal Dementias (ISFTD) 2021
Live Stream: March 3 - 5, 2021
Course# MNR21005

Live Stream Schedule

** All time indicated below are Pacific Standard Time **

Wednesday, March 3, 2021  
7:15am Zoom Registration and Login    
7:30 Conference Overview Facundo Manes MD, PhD, INECO/Favaloro Univ. Argentina  
    Bruce Miller, MD, UCSF, USA; Brad Boeve, MD, Mayo Clinic Rochester, USA  
    Susan Dickinson, MSGC, Association for Frontotemporal Degeneration (AFTD)  
7:45 President Lecture Rosa Rademakers, PhD  
    Antwerp Univ, Belgium  
8:00 FTD & Society Facundo Manes, MD, PhD INECO/Favaloro University Argentina   
  Introduction to FTD    
  Session Moderator: Chiadi Onyike, MD, MHS    
8:15 Evolving Issues in FTD Bruce Miller, MD  
    UCSF, USA  
8:30 Differentiating the Behavioral Variant of Frontotemporal Dementia from Primary Psychiatric Disorders Chiadi Onyike, MD, MHS  
    Johns Hopkins Univ, USA  
8:45 Magnetoencephalography (MEG) in FTD, From Mechanisms to Experimental Medicine James Rowe, MD, PhD   
    Univ of Cambridge UK  
9:00 Measuring Behavior for Diagnosis of bvFTD Kate Rankin, PhD  Slides
    UCSF, USA  
9:15 Innovative Measures for Assessing Social Cognition Fiona Kumfor, PhD   
    Univ. of Sydney  
9:30 Question & Answer    
9:45 Anterior Temporal Lobe: Left Versus Right Marsel Mesulam, MD, Northwestern Univ, USA  
10:00 The Nonfluent/Agrammatic Progressive Aphasia Spectrum Marilu Gorno-Tempini, MD, PhD   
    UCSF, USA  
10:15 FTD and the Connectome Murray Grossman, MDCM  
    Univ of Pennsylvania, USA  
10:30 Longitudinal Studies of FTD Howard Rosen, MD    
    UCSF, USA  
10:45 Question & Answer    
11:00 Break    
  Biomarkers & Treatments for FTD    
  Session Moderator: Emily Rogalski, PhD    
11:30 Molecular Therapies for FTD Adam Boxer, MD, PhD    
    UCSF, USA  
11:45 Overview of Fluid Biomarkers for Neurodegenerative Dementias Henrik Zetterberg, MD, PhD   
    Univ of Gothenburg, Sweden  
12:00pm Endpoints for FTD Clinical Trials Adam Staffaroni, PhD  
    UCSF, USA  
12:15 Primary Progressive Aphasia: Nonpharmacologic Intervention Progress and Opportunities Emily Rogalski, PhD  
    Northwestern Univ, USA  
12:30 Pharm and Nonpharm Management of Behaviors in bvFTD Elizabeth Finger, MD    
    Univ of Western Ontario, Canada  
1:00 Question & Answer    
1:15pm Adjourn    
Thursday, March 4, 2021  
**All times are in Pacific Standard Time, Live Sessions  
7:30am Zoom Registration and Login    
  Genetics from Gene to Molecule    
  Session Moderator: Manuela Neumann, MD, PhD    
7:45 Genetic Discovery in Diverse Patients Diagnosed with FTD Jennifer S. Yokoyama, PhD  
    UCSF, USA  
8:00 Tau in FTD Maria Spillantini, PhD    
    Univ. of Cambridge, UK  
8:15 C9orf72 Diagnosis and Therapies Leonard Petrucelli, PhD   
    Mayo Clinic Florida, USA  
8:30 Neuroimaging of Genetic Cohorts Suzee Lee, MD  
    UCSF, USA  
8:45 FUS in ALS and FTLD Manuela Neumann, MD  
    Univ of Tübingen, Germany  
9:00 GRN Gene to Syndrome Isabelle LeBer, MD, PhD Hôpitaux de Paris, Hôpital Pitié-Salpêtrière, France  
9:15 Question & Answer     
  Neuropathology    
  Session Moderator: William Seeley, MD    
9:30 Tau Filaments in Frontotemporal Degeneration and Alzheimer Disease: Molecular Conformers Revealed by Cryo-Electron Microscopy Bernardino Ghetti, MD  
    Indiana Univ, USA  
9:45 Copathologies in FTD Syndromes (Neuropathologic Issues) Glenda Halliday, PhD, FAAHMS    
    Univ. of Sydney, Australia  
10:00 FTD Neuropathology Update Ian Mackenzie, MD   
    Univ of British Columbia, Canada  
10:15 Neuron Type-specific TDP-43 Pathobiology: Gain or Loss of Function? William Seeley, MD 
UCSF, USA
 
10:30 Late Onset FTLD-TDP and LATE Keith A. Josephs, MD, MST, MSc    
    Mayo Clinic Rochester, USA  
10:45 Question & Answer    
11:00 Break    
  Clinical FTD    
  Session Moderator Irene Litvan, MD, FAAN, FANA    
11:15 Cognitive and Behavioural Dimensions of ALS Orla Hardiman, BSc, MD, FTCD, MRIA   
    Trinity College Dublin, Ireland  
11:30 Motor Changes in FTD Spectrum Brad Dickerson, MD  
    Harvard Medical School, USA  
11:45 Multiple Corticobasal Degeneration and PSP Presentations Irene Litvan, MD, FAAN, FANA
UCSD, USA
 
12:00pm Social and Legal Issues in FTLD  Mario Mendez, MD, PhD   
    UCLA, USA  
12:15 Lille-Paris ICFTD 2022 / 2nd ISFTD Meeting Florence Pasquier, MD, PhD    
    Univ de Lille, France   
12:30 Question & Answer    
12:45pm Adjourn    
Friday March 5, 2021  
**All times are in Pacific Standard Time, Live Sessions  
7:45am Zoom Registration and Login    
Latin America Session of the 1st International Society for Frontotemporal Dementia  
  Introduction to FTD Session    
  Moderator Facundo Manes, MD, PhD    
8:00 FTD and Society Facundo Manes, MD, PhD INECO/Favaloro Univ. Argentina  
8:15 Advances in FTD Bruce Miller, MD   
    UCSF, USA  
  FTD the Clinical Syndromes    
8:30 bvFTD Leonel T. Takada, MD, PhD   
    Univ.of São Paulo, Brazil  
8:50 Bilingualism in FTD   Jessica de Leon, MD   
    UCSF, USA   
9:10 Neuropathologic Patterns in Primary Progressive Aphasia Marsel Mesulam, MD  
    Northwestern Univ, USA  
  Northwestern University, USA    
9:30 Artificial Intelligence Approaches to Language Adolfo Garcia, PhD   
    REDLAT Argentina  
9:50 Panel Discussion: FTD Diagnosis in Low Education Populations Ricardo Nitrini, MD   
    Department of Neurology, São Paulo, Brazil   
    Nilton Custodio, MD, PhD   
    Institute of Neurosciences   
    Lima, Peru  
    Elisa de Paula Franca Resende, MD, PhD, GBHI   
    Francisco Lopera, MD   
    Univ. de Antioquia, Medellín, Colombia   
10:20 Break    
REDLAT Session  
Session Moderator: Agustin Ibanez, PhD  
10:40 REDLAT Overview Agustin Ibanez, PhD   
    REDLAT Argentina  
10:55 REDLAT Clinical Organization Andrea Slachevsky, MD PhD  
    GERO and Univ. of Chile, Chile  
  FTD Genetics in South America Claudia Ramos, MD   
11:10   Univ. de Antioquia - Medellín, Colombia  
11:30 FTD Mutations in Bogota, Colombia Diana Matallana, PhD  
    Universidad Javeriana, Bogotá, Colombia.  
11:50am Lunch    
Special Topics in FTD Session  
Moderator Stefanie Pina Escudero, MD  
1:00pm Emotion in FTD Virginia Sturm, PhD   
    UCSF, USA  
1:20 Imaging-Genomics in FTD Corey McMillan, PhD   
    Univ of Pennsylvania, USA  
1:40 Social Determinants of Health Stefanie Piña Escudero, MD  
    GHBI  
2:00 Sex Differences in FTD Ignacio Illán-Gala, MD, PhD   
    Santa Creu i Sant Pau Hospital Barcelona, Spain  
2:20 Discussion    
2:30 Break    
Bluefield Symposium Clinical Trials & Progranulin Session   
Moderator Rosa Rademakers, PhD  
2:50 Progranulin Genetics Rosa Rademakers, PhD   
    Antwerp Univ, Belgium  
3:10 Molecular Pathology of Progranulin Deficiency: From Mouse to Human Eric Huang, MD, PhD   
    UCSF, USA  
3:30 Progranulin Families John C. van Swieten, MD, PhD  Erasmus MC-University, Netherlands  
3:50 GRN Models, Lipids and the Lysosome Robert V. Farese, MD   
    Harvard Medical School, USA  
4:10 Progranulin, Multi-granulin Fragments and Granulins: Differential Modifiers of Lysosome Function Aimee Kao, MD, PhD   
    UCSF, USA  
4:30 Clinical Trials for Progranulin Julio Rojas, MD, PhD   
    UCSF, USA  
4:50pm Adjourn    
PRE-RECORDED SESSIONS  
Time Title Faculty Recordings
  International Consortium for FTD    
15 min GENFI Jonathan Rohrer, FRCP, PhD 
Univ College London, UK
Video
15 min ALLFTD Brad Boeve, MD 
Mayo Clinic Rochester, USA
Video
15 min Japanese Frontotemporal Dementia Consortium Manabu Ikeda, MD, PhD 
Osaka Univ, Japan
Video
15 min Latin American Initiative ReDLat Agustin Ibanez, PhD 
REDLAT
Video
15 min Australia, Dominantly Inherited Non-Alzheimer Dementias Olivier Piguet, PhD 
Univ of Sydney, Australia
Video
15 min Neuropsychiatric International Consortium for FTD (NIC-FTD) Yolande Pijnenburg, MD, PhD
Amsterdam UMC, Netherlands 
Video
  Special Topics    
15 min FTD Diagnosis in Low Education Populations Sonia Brucki, MD, PhD
University of Sao Paulo
Video
15 min iPSC Derived Neurons in FTD  Selina Wray, PhD
Univ. College, England
Video
15 min Neuropsychological Assessment in FTD: Practical Considerations Katya Rascovsky, PhD 
Univ of Pennsylvania, USA
Video
15 min Bilingualism and Diagnosis of FTD                                                                           Suvarna Alladi, MD 
Department of Neurology, Bangalore, India
Video
15 min Misdiagnosis of FTD  Shunichiro Shinagawa, MD, PhD
Jikei Univ, Tokyo, Japan
Video
15 min Primary Progressive Aphasia in Chinese Language Boon Lead Tee, MD
GBHI 
Video
15 min Tests of Frontal Lobe Function Bruno Dubois, MD, PhD  
Institute of the Salpétrière University Hospital at Paris
Video
15 min Late Onset FTD Sang Won Seo, MD, PhD Sungkyunkwan University School of Medicine, South Korea Video
  Family Track    
20 min Introduction Bruce Miller, MD 
UCSF, USA
 
  Association for Frontotemporal Degeneration (AFTD)    
    Susan Dickinson, MSGC Video
    Association for Frontotemporal Degeneration (AFTD)  
15 min Experiences of Caring for a Person Living with FTD Jennifer Merrilees, RN, PhD 
UCSF, USA
Video
20 min Approach to Caregivers in Latin America Teresa Torralva PHD  Video
    Julian Bustin, MD   
    INECO, Argentina  
    Facundo Manes,MD PhD INECO/Favaloro Univ. Argentina